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In animals, nicotine can cause a developing brain to have an increased number of connections between cells in the cerebral cortex region, says Picciotto

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Since the highest tar-and-nicotine content is to be found, generally speaking, in the best-selling brands of cigarettes, a good argument can be made for federal health regulations that would require systematic further reductions of the tar-and-nicotine content of all cigarettes over, say, a ten-year period