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Common physical symptoms include: Dilated pupils that remain enlarged even in bright light conditions Rapid and significant weight loss caused by appetite suppression Chronic insomnia and irregular sleep patterns despite exhaustion Elevated heart rate and persistently high blood pressure Excessive sweating unrelated to heat or physical activity Teeth grinding (bruxism) and jaw clenching, particularly common with MDMA and meth Dental deterioration known as meth mouth in long-term methamphetamine users Nosebleeds, nasal damage, and chronic congestion in cocaine users Psychological and Cognitive Symptoms The psychological toll of stimulant addiction is often the most debilitating aspect of the disorder
As we came back down our road, Troy was in his driveway getting ready to leave
6,17-22 Reduced nicotine in cigarettes will likely accelerate switching to less harmful products
Mucocutaneous features of Ehlers-Danlos syndrome Classic Ehlers-Danlos syndrome (MIM 130000) has the additional cutaneous features: Soft velvety skin Normal skin recoil after stretching Hyperlinear loose skin on the palms and soles Lax skin around the eyes and face forming folds in later life Lack of stretch marks in pregnancy Wounds heal slowly to leave wide 'cigarette-paper' scars Molluscoid pseudotumours - spongy blue-grey lumps over pressure points and scars Calcified spheroids - small, firm, subcutaneous nodules on forearms and shins Pigmentation following repeated bruising of easily traumatised sites Piezogenic pedal papules
Niederdeppe, J., Fiore, M
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