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[Lipoic acid as a means of metabolic therapy of open-angle glaucoma]

Kovalzon V.M., Strekalova T.V

pAKT-Ser473, AKT, PPAR, PGC1, CPT1, Nrf2, UCP1 and pP38 antibodies were purchased from Cell Signaling Technology (Beverly, MA, USA)

Studies published in Biochemical Pharmacology show that NNMT expression increases significantly with aging in skeletal muscle tissue and correlates with impaired muscle stem cell function and reduced regenerative capacity

The functional prediction performed using phylogenetic investigation of communities by reconstruction of unobserved states (PICRUSt) and Kyoto encyclopedia of genes and genomes (KEGG) implicated that the depleted gut microbiome was associated with metabolic pathways, including those related to carbohydrates, butanoate, and amino acids (Supplementary Fig