Direct effects GLP-1R mRNA and protein have been detected in human renal vascular smooth muscle cells of afferent and efferent arterioles, interlobular and arcuate arteries, and juxtaglomerular and proximal tubular cells [56]
Pentose phosphate pathway (PPP)
Tirzepatide adds a second mechanism by also activating GIP receptors, which amplifies its metabolic effects
If you live in Louisiana, Mississippi, New Mexico, Rhode Island, Kansas or West Virginia, you will be required by state law to perform a video consult with our medical team
Other episodes in this series The Pharmacists Voice Podcast Episode 328, Pronunciation Series Episode 54 (nalmefene) The Pharmacists Voice Podcast episode 250, pronunciation series episode 22 (metformin/Glucophage) The Pharmacists Voice Podcast episode 215, pronunciation series episode 16 (mifepristone and misoprostol) The Pharmacists Voice Podcast episode 184, pronunciation series episode 10 (phenytoin and isotretinoin) The Pharmacists Voice Podcast episode 180, pronunciation series episode 9 Apretude (cabotegravir) The Pharmacists Voice Podcast episode 159, pronunciation series episode 6 (talimogene laherparepvec or T-VEC) The Pharmacists Voice Podcast episode 155, pronunciation series episode 5 Trulicity (dulaglutide) The Pharmacists Voice Podcast episode 148, pronunciation series episode 4 Besponsa (inotuzumab ozogamicin) The Pharmacists Voice Podcast episode 142, pronunciation series episode 3 Zolmitriptan and Zokinvy The Pharmacists Voice Podcast episode 138, pronunciation series episode 2 Molnupiravir and Taltz The Pharmacists Voice Podcast episode 134, pronunciation series episode 1 Eszopiclone and Qulipta
